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Annals of Surgery Mar 1976A total of 239 surgically treated patients with primary endocarditis were reviewed both from the literature and from our own experience. The age range was 10 to 74 years... (Review)
Review
A total of 239 surgically treated patients with primary endocarditis were reviewed both from the literature and from our own experience. The age range was 10 to 74 years with a male to female ratio of 3:1. A wide variety of organisms was found. However, as a group, gram positive organisms predominate. The onset of congestive failure was the major indication for surgery. The aortic valve was predominantly involved with the mitral valve running a distant second. The hospital mortality rate was 20% and the late mortality rate was 6.7% with an overall mortality of 26.7%. The prognosis in infective endocarditis when congestive failure develops, even in the presence of antibiotic therapy, is poor (79-89% mortality). In view of this poor prognosis, an aggressive attitude with regard to early surgical intervention can greatly improve the outcome of valvular endocarditis.
Topics: Adolescent; Adult; Aged; Endocarditis, Bacterial; Female; Heart Valve Prosthesis; Heart Valves; Humans; Male; Middle Aged
PubMed: 769712
DOI: 10.1097/00000658-197603000-00013 -
Archivos de Cardiologia de Mexico Jan 2022Infective endocarditis (IE) is an infection with a poor prognosis, and an associated in-hospital mortality of at least 25%. Optimal therapy of IE requires long-term...
BACKGROUND AND OBJECTIVE
Infective endocarditis (IE) is an infection with a poor prognosis, and an associated in-hospital mortality of at least 25%. Optimal therapy of IE requires long-term effective antibiotic therapy and valve surgery in many cases. The aim of this study was to review the demographics, bacteriology, and outcomes of patients with IE admitted to a tertiary referral center in Mexico City, over a 10-year period.
METHODS
Retrospective cohort study of patients admitted at Instituto Nacional Salvador Zubiran with a new diagnosis of IE over a 10-year period, from January 2009 to January 2019. Patients who met the definition for definitive diagnosis of infective endocarditis according to the modified Duke criteria were included in the study.
RESULTS
There were 62 patients (50.85 ± 17.46 years, 40.3% females) with IE. The culprit microorganism was identified in all cases, with Staphylococcus aureus being the most frequently found (34%). Valve surgery was performed in 58.1%, while 41.9% only received medical treatment. The mortality rate was 25.8% at 30 days and 41.9% at 12 months. Comparing the surgical and medical treatment groups, we found that 50% and 36% in each group, respectively, had died within 12 months of admission.
CONCLUSIONS
Our center has a high prevalence of health care-associated endocarditis, mostly related to the presence of intravascular access devices. Most of the patients had a surgical indication. Patients with type 2 diabetes mellitus and decreased right ventricular systolic function had an increased mortality rate at 12 months.
Topics: Diabetes Mellitus, Type 2; Endocarditis; Endocarditis, Bacterial; Female; Hospital Mortality; Humans; Male; Retrospective Studies; Staphylococcal Infections
PubMed: 34635860
DOI: 10.24875/ACM.20000467 -
British Medical Journal Mar 1963
Topics: Chorea; Endocarditis; Endocarditis, Bacterial; Endocarditis, Subacute Bacterial; Humans
PubMed: 13934389
DOI: 10.1136/bmj.1.5334.861 -
The Journal of Thoracic and... Apr 2021
Topics: Databases, Factual; Endocarditis; Endocarditis, Bacterial; Humans; Surgeons; Tricuspid Valve
PubMed: 32007250
DOI: 10.1016/j.jtcvs.2019.11.066 -
Journal of the American College of... Jul 2020
Topics: Anti-Bacterial Agents; Endocarditis; Endocarditis, Bacterial; Humans
PubMed: 32616161
DOI: 10.1016/j.jacc.2020.05.049 -
Cleveland Clinic Journal of Medicine Aug 2023
Topics: Humans; Endocarditis; Endocarditis, Bacterial
PubMed: 37527876
DOI: 10.3949/ccjm.90b.08023 -
Future Cardiology Nov 2022Cardiac implantable electronic device infective endocarditis is a serious infection with poor prognosis. The systematic review of the literature was conducted using... (Review)
Review
Cardiac implantable electronic device infective endocarditis is a serious infection with poor prognosis. The systematic review of the literature was conducted using searches from the various databases. We included studies published between January 2010 and June 2021. A total of 35 articles met the inclusion criteria. Patients were approximately 70 years old and an average of 71.2% of patients were male. The most common presenting feature was a fever. The modified Duke criteria was used to aid diagnosis. Management entailed extraction of the cardiac implantable electronic device in 80.5% of the studies. The overall mortality rates ranged from 4 to 36%. The most frequently isolated organism was . Cardiac implantable electronic device infective endocarditis needs timely diagnosis and effective management for promising outcomes.
Topics: Humans; Male; Aged; Female; Pacemaker, Artificial; Defibrillators, Implantable; Endocarditis, Bacterial; Endocarditis; Electronics
PubMed: 36073290
DOI: 10.2217/fca-2021-0155 -
Heart (British Cardiac Society) Jul 2006Infective endocarditis (IE) is an evolving disease with a persistently high mortality and morbidity, even in the modern era of advanced diagnostic imaging, improved... (Review)
Review
Infective endocarditis (IE) is an evolving disease with a persistently high mortality and morbidity, even in the modern era of advanced diagnostic imaging, improved antimicrobial chemotherapy, and potentially curative surgery. Despite these improvements in health care, the incidence of the disease has remained unchanged over the past two decades and may even be increasing. Chronic rheumatic heart disease is now an uncommon antecedent, whereas degenerative valve disease of the elderly, mitral valve prolapse, intravenous drug misuse, preceding valve replacement, and vascular instrumentation have become increasingly common, coinciding with an increase in staphylococcal infections and those caused by fastidious organisms. The current understanding of this difficult condition is reviewed and recent developments in medical and surgical management are updated.
Topics: Endocarditis, Bacterial; Humans
PubMed: 16216860
DOI: 10.1136/hrt.2005.067256 -
Journal of the American Veterinary... May 2019
Topics: Animals; Dog Diseases; Dogs; Endocarditis, Bacterial; Female
PubMed: 31039094
DOI: 10.2460/javma.254.10.1155 -
British Heart Journal Mar 1987
Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; History, 20th Century; Humans
PubMed: 3552004
DOI: 10.1136/hrt.57.3.211